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Inducible T-cell costimulator est une protéine point de contrôle immunitaire codée chez l'homme gène ICOS. CD278 ou ICOS (Inducible T-cell COStimulator) est une molécule de costimulation de la superfamille CD28 qui est exprimée à la surface des lymphocytes T activés. Elle est considérée comme importante pour les cellules Th2 en particulier.

Property Value
dbo:abstract
  • Inducible T-cell costimulator est une protéine point de contrôle immunitaire codée chez l'homme gène ICOS. CD278 ou ICOS (Inducible T-cell COStimulator) est une molécule de costimulation de la superfamille CD28 qui est exprimée à la surface des lymphocytes T activés. Elle est considérée comme importante pour les cellules Th2 en particulier. (fr)
  • Inducible T-cell costimulator est une protéine point de contrôle immunitaire codée chez l'homme gène ICOS. CD278 ou ICOS (Inducible T-cell COStimulator) est une molécule de costimulation de la superfamille CD28 qui est exprimée à la surface des lymphocytes T activés. Elle est considérée comme importante pour les cellules Th2 en particulier. (fr)
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prop-fr:année
  • 2002 (xsd:integer)
  • 2003 (xsd:integer)
prop-fr:auteurs
  • Ling V, Wu PW, Finnerty HF, Agostino MJ, Graham JR, Chen S, Jussiff JM, Fisk GJ, Miller CP, Collins M (fr)
  • Witsch EJ, Peiser M, Hutloff A, Büchner K, Dorner BG, Jonuleit H, Mages HW, Kroczek RA (fr)
  • Machado RD, Pauciulo MW, Fretwell N, Veal C, Thomson JR, Vilariño Güell C, Aldred M, Brannon CA, Trembath RC, Nichols WC (fr)
  • Ling V, Wu PW, Finnerty HF, Bean KM, Spaulding V, Fouser LA, Leonard JP, Hunter SE, Zollner R, Thomas JL, Miyashiro JS, Jacobs KA, Collins M (fr)
  • Riley JL, Mao M, Kobayashi S, Biery M, Burchard J, Cavet G, Gregson BP, June CH, Linsley PS (fr)
  • Flesch IE (fr)
  • Haimila KE, Partanen JA, Holopainen PM (fr)
  • Lee YH, Ji JD, Sohn J, Song GG (fr)
  • Shilling RA, Bandukwala HS, Sperling AI (fr)
  • Wang S, Zhu G, Tamada K, Chen L, Bajorath J (fr)
  • Grimbacher B, Hutloff A, Schlesier M, Glocker E, Warnatz K, Dräger R, Eibel H, Fischer B, Schäffer AA, Mages HW, Kroczek RA, Peter HH (fr)
  • Aicher A, Hayden-Ledbetter M, Brady WA, Pezzutto A, Richter G, Magaletti D, Buckwalter S, Ledbetter JA, Clark EA (fr)
  • Breitfeld D, Ohl L, Kremmer E, Ellwart J, Sallusto F, Lipp M, Förster R (fr)
  • Beier KC, Hutloff A, Dittrich AM, Heuck C, Rauch A, Büchner K, Ludewig B, Ochs HD, Mages HW, Kroczek RA (fr)
  • Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (fr)
  • Wang S, Zhu G, Chapoval AI, Dong H, Tamada K, Ni J, Chen L (fr)
  • Tezuka K, Tsuji T, Hirano D, Tamatani T, Sakamaki K, Kobayashi Y, Kamada M (fr)
  • Ling V, Wu PW, Finnerty HF, Agostino MJ, Graham JR, Chen S, Jussiff JM, Fisk GJ, Miller CP, Collins M (fr)
  • Witsch EJ, Peiser M, Hutloff A, Büchner K, Dorner BG, Jonuleit H, Mages HW, Kroczek RA (fr)
  • Machado RD, Pauciulo MW, Fretwell N, Veal C, Thomson JR, Vilariño Güell C, Aldred M, Brannon CA, Trembath RC, Nichols WC (fr)
  • Ling V, Wu PW, Finnerty HF, Bean KM, Spaulding V, Fouser LA, Leonard JP, Hunter SE, Zollner R, Thomas JL, Miyashiro JS, Jacobs KA, Collins M (fr)
  • Riley JL, Mao M, Kobayashi S, Biery M, Burchard J, Cavet G, Gregson BP, June CH, Linsley PS (fr)
  • Flesch IE (fr)
  • Haimila KE, Partanen JA, Holopainen PM (fr)
  • Lee YH, Ji JD, Sohn J, Song GG (fr)
  • Shilling RA, Bandukwala HS, Sperling AI (fr)
  • Wang S, Zhu G, Tamada K, Chen L, Bajorath J (fr)
  • Grimbacher B, Hutloff A, Schlesier M, Glocker E, Warnatz K, Dräger R, Eibel H, Fischer B, Schäffer AA, Mages HW, Kroczek RA, Peter HH (fr)
  • Aicher A, Hayden-Ledbetter M, Brady WA, Pezzutto A, Richter G, Magaletti D, Buckwalter S, Ledbetter JA, Clark EA (fr)
  • Breitfeld D, Ohl L, Kremmer E, Ellwart J, Sallusto F, Lipp M, Förster R (fr)
  • Beier KC, Hutloff A, Dittrich AM, Heuck C, Rauch A, Büchner K, Ludewig B, Ochs HD, Mages HW, Kroczek RA (fr)
  • Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (fr)
  • Wang S, Zhu G, Chapoval AI, Dong H, Tamada K, Ni J, Chen L (fr)
  • Tezuka K, Tsuji T, Hirano D, Tamatani T, Sakamaki K, Kobayashi Y, Kamada M (fr)
prop-fr:bande
  • 33.200000 (xsd:double)
prop-fr:bras
  • q (fr)
  • q (fr)
prop-fr:chromosome
  • 2 (xsd:integer)
prop-fr:date
  • Mar 2002 (fr)
  • Oct 2006 (fr)
  • mai 2000 (fr)
  • Apr 2002 (fr)
  • Dec 2000 (fr)
  • Dec 2001 (fr)
  • Dec 2002 (fr)
  • Feb 2000 (fr)
  • Mar 2003 (fr)
  • Oct 2000 (fr)
  • Sep 2000 (fr)
  • Sep 2002 (fr)
  • Mar 2002 (fr)
  • Oct 2006 (fr)
  • mai 2000 (fr)
  • Apr 2002 (fr)
  • Dec 2000 (fr)
  • Dec 2001 (fr)
  • Dec 2002 (fr)
  • Feb 2000 (fr)
  • Mar 2003 (fr)
  • Oct 2000 (fr)
  • Sep 2000 (fr)
  • Sep 2002 (fr)
prop-fr:doi
  • 10.100200 (xsd:double)
  • 10.100600 (xsd:double)
  • 10.100700 (xsd:double)
  • 10.101600 (xsd:double)
  • 10.103800 (xsd:double)
  • 10.107300 (xsd:double)
  • 10.108400 (xsd:double)
  • 10.404900 (xsd:double)
prop-fr:journal
  • Blood (fr)
  • Proceedings of the National Academy of Sciences of the United States of America (fr)
  • Journal of Biological Regulators and Homeostatic Agents (fr)
  • Biochemical and Biophysical Research Communications (fr)
  • Clinical Immunology (fr)
  • Clinical Rheumatology (fr)
  • European Journal of Immunology (fr)
  • Genomics (fr)
  • Immunogenetics (fr)
  • Journal of Immunology (fr)
  • Nature Immunology (fr)
  • The Journal of Experimental Medicine (fr)
  • Blood (fr)
  • Proceedings of the National Academy of Sciences of the United States of America (fr)
  • Journal of Biological Regulators and Homeostatic Agents (fr)
  • Biochemical and Biophysical Research Communications (fr)
  • Clinical Immunology (fr)
  • Clinical Rheumatology (fr)
  • European Journal of Immunology (fr)
  • Genomics (fr)
  • Immunogenetics (fr)
  • Journal of Immunology (fr)
  • Nature Immunology (fr)
  • The Journal of Experimental Medicine (fr)
prop-fr:nom
  • ICOS (fr)
  • ICOS (fr)
prop-fr:numéro
  • 1 (xsd:integer)
  • 2 (xsd:integer)
  • 3 (xsd:integer)
  • 4 (xsd:integer)
  • 6 (xsd:integer)
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  • 1028 (xsd:integer)
  • 1033 (xsd:integer)
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  • 2808 (xsd:integer)
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prop-fr:pmc
  • 129347 (xsd:integer)
  • 139241 (xsd:integer)
  • 2193094 (xsd:integer)
  • 2193694 (xsd:integer)
prop-fr:pmid
  • 10657606 (xsd:integer)
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  • 12456021 (xsd:integer)
  • 12477932 (xsd:integer)
  • 12577056 (xsd:integer)
  • 16790364 (xsd:integer)
prop-fr:symbole
  • ICOS (fr)
  • ICOS (fr)
prop-fr:synonymes
  • AILIM, CD278, CVID1, inducible T-cell co-stimulator, inducible T-cell costimulator, inducible T cell costimulator (fr)
  • AILIM, CD278, CVID1, inducible T-cell co-stimulator, inducible T-cell costimulator, inducible T cell costimulator (fr)
prop-fr:titre
  • Assembly and annotation of human chromosome 2q33 sequence containing the CD28, CTLA4, and ICOS gene cluster: analysis by computational, comparative, and microarray approaches (fr)
  • Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency (fr)
  • Regulation of T:B cell interactions by the inducible costimulator molecule: does ICOS "induce" disease? (fr)
  • Cutting edge: identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor (fr)
  • Genetic polymorphism of the human ICOS gene (fr)
  • Inducible costimulator (fr)
  • Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production (fr)
  • Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS (fr)
  • Ligand binding sites of inducible costimulator and high avidity mutants with improved function (fr)
  • Polymorphsims of CTLA-4 exon 1 +49, CTLA-4 promoter -318 and Fas promoter -670 in spondyloarthropathies (fr)
  • A physical and transcript map based upon refinement of the critical interval for PPH1, a gene for familial primary pulmonary hypertension. The International PPH Consortium (fr)
  • Characterization of human inducible costimulator ligand expression and function (fr)
  • Induction, binding specificity and function of human ICOS (fr)
  • Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences (fr)
  • Identification and characterization of rat AILIM/ICOS, a novel T-cell costimulatory molecule, related to the CD28/CTLA4 family (fr)
  • ICOS and CD28 reversely regulate IL-10 on re-activation of human effector T cells with mature dendritic cells (fr)
  • Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors (fr)
  • Assembly and annotation of human chromosome 2q33 sequence containing the CD28, CTLA4, and ICOS gene cluster: analysis by computational, comparative, and microarray approaches (fr)
  • Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency (fr)
  • Regulation of T:B cell interactions by the inducible costimulator molecule: does ICOS "induce" disease? (fr)
  • Cutting edge: identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor (fr)
  • Genetic polymorphism of the human ICOS gene (fr)
  • Inducible costimulator (fr)
  • Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production (fr)
  • Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS (fr)
  • Ligand binding sites of inducible costimulator and high avidity mutants with improved function (fr)
  • Polymorphsims of CTLA-4 exon 1 +49, CTLA-4 promoter -318 and Fas promoter -670 in spondyloarthropathies (fr)
  • A physical and transcript map based upon refinement of the critical interval for PPH1, a gene for familial primary pulmonary hypertension. The International PPH Consortium (fr)
  • Characterization of human inducible costimulator ligand expression and function (fr)
  • Induction, binding specificity and function of human ICOS (fr)
  • Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences (fr)
  • Identification and characterization of rat AILIM/ICOS, a novel T-cell costimulatory molecule, related to the CD28/CTLA4 family (fr)
  • ICOS and CD28 reversely regulate IL-10 on re-activation of human effector T cells with mature dendritic cells (fr)
  • Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors (fr)
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prop-fr:wikiPageUsesTemplate
dct:subject
rdf:type
rdfs:comment
  • Inducible T-cell costimulator est une protéine point de contrôle immunitaire codée chez l'homme gène ICOS. CD278 ou ICOS (Inducible T-cell COStimulator) est une molécule de costimulation de la superfamille CD28 qui est exprimée à la surface des lymphocytes T activés. Elle est considérée comme importante pour les cellules Th2 en particulier. (fr)
  • Inducible T-cell costimulator est une protéine point de contrôle immunitaire codée chez l'homme gène ICOS. CD278 ou ICOS (Inducible T-cell COStimulator) est une molécule de costimulation de la superfamille CD28 qui est exprimée à la surface des lymphocytes T activés. Elle est considérée comme importante pour les cellules Th2 en particulier. (fr)
rdfs:label
  • CD278 (ca)
  • CD278 (fr)
  • ICOS (uk)
  • كتلة التمايز 278 (arz)
  • CD278 (ca)
  • CD278 (fr)
  • ICOS (uk)
  • كتلة التمايز 278 (arz)
rdfs:seeAlso
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
is oa:hasTarget of
is foaf:primaryTopic of
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