En neuroscience, la neuromodulation est le processus par lequel plusieurs classes de neurotransmetteurs du système nerveux régulent plusieurs populations de neurones.

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  • En neuroscience, la neuromodulation est le processus par lequel plusieurs classes de neurotransmetteurs du système nerveux régulent plusieurs populations de neurones. À l'opposé de la transmission synaptique, dans laquelle un neurone présynaptique influence directement un pair postsynaptique, les transmetteurs neuromodulateurs secrétés par un groupe restreint de neurones se diffusent à travers le système nerveux, ayant un impact sur multiples neurones.Parmi les neuromodulateurs on trouve par exemple la dopamine, la sérotonine, l'acétylcholine, et l'histamine, mais aussi bien d'autres.
  • Neuromodulation is the physiological process by which a given neuron uses one or more neurotransmitters to regulate diverse populations of neurons. This is in contrast to classical synaptic transmission, in which one presynaptic neuron directly influences a single postsynaptic partner. Neuromodulators secreted by a small group of neurons diffuse through large areas of the nervous system, affecting multiple neurons. Examples of neuromodulators include dopamine, serotonin, acetylcholine, histamine and others.Neuromodulation can be conceptualized as a neurotransmitter that is not reabsorbed by the pre-synaptic neuron or broken down into a metabolite. Such neuromodulators end up spending a significant amount of time in the cerebrospinal fluid (CSF), influencing (or "modulating") the activity of several other neurons in the brain. For this reason, some neurotransmitters are also considered to be neuromodulators, such as serotonin and acetylcholine.[citation needed]Neuromodulation is often contrasted with classical fast synaptic transmission. In both cases the transmitter acts on local postsynaptic receptors, but in neuromodulation, the receptors are typically G-protein coupled receptors while in classical chemical neurotransmission, they are ligand-gated ion channels. Neurotransmission that involves metabotropic receptors (like G-protein linked receptors) often also involves voltage-gated ion channels, and is relatively slow. Conversely, neurotransmission that involves exclusively ligand-gated ion channels is much faster.A related distinction is also sometimes drawn between modulator and driver synaptic inputs to a neuron, but here the emphasis is on modulating ongoing neuronal spiking versus causing that spiking.
  • Neuromodeladores são substancias que são importantes para a actividade neuronal, mas que não actuam de modo trans-sináptico como os neurotransmissores, possuindo uma acção mais hormonal.
  • Un neuromodulatore è una sostanza naturalmente secreta dal cervello, che agisce come neurotrasmettitore modulando l'attività della cellula nervosa, tranne per il fatto che la sua azione non è limitata alla fessura sinaptica ma si diffonde in tutto il fluido extracellulare circostante.Tra questi vi sono acetilcolina, dopamina, noradrenalina e serotonina.
  • Neuromodulatoren sind chemische Substanzen, die die Arbeitsweise des Nervensystems beeinflussen. Sie können vom Körper selbst produziert werden und sind für die normale, physiologische Arbeitsweise des Gehirns unverzichtbar. Neuromodulatoren sind aber auch zahlreiche pharmakologisch aktive Substanzen, die dem Körper von außen zugeführt werden und als Medikamente oder Drogen wirken. Diesen Substanzen übergeordnet ist die Synapse – eine anatomische Struktur, die die Neuromodulation erst ermöglicht. Hier werden elektrische Impulse, sog. Aktionspotentiale in eine chemische Signalübertragung umgewandelt. Neuromodulatorische Stoffe sind:
  • Neuromodulatie is een proces waarbij neurofysiologische signalen actief geïnitieerd of beïnvloed worden met als doel de functie en werking van het zenuwstelsel te beïnvloeden. Neuromodulatie kan gebruikt worden om therapeutische effecten te bereiken, waarbij een verloren gegane functie wordt hersteld.
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  • En neuroscience, la neuromodulation est le processus par lequel plusieurs classes de neurotransmetteurs du système nerveux régulent plusieurs populations de neurones.
  • Neuromodeladores são substancias que são importantes para a actividade neuronal, mas que não actuam de modo trans-sináptico como os neurotransmissores, possuindo uma acção mais hormonal.
  • Un neuromodulatore è una sostanza naturalmente secreta dal cervello, che agisce come neurotrasmettitore modulando l'attività della cellula nervosa, tranne per il fatto che la sua azione non è limitata alla fessura sinaptica ma si diffonde in tutto il fluido extracellulare circostante.Tra questi vi sono acetilcolina, dopamina, noradrenalina e serotonina.
  • Neuromodulatie is een proces waarbij neurofysiologische signalen actief geïnitieerd of beïnvloed worden met als doel de functie en werking van het zenuwstelsel te beïnvloeden. Neuromodulatie kan gebruikt worden om therapeutische effecten te bereiken, waarbij een verloren gegane functie wordt hersteld.
  • Neuromodulation is the physiological process by which a given neuron uses one or more neurotransmitters to regulate diverse populations of neurons. This is in contrast to classical synaptic transmission, in which one presynaptic neuron directly influences a single postsynaptic partner. Neuromodulators secreted by a small group of neurons diffuse through large areas of the nervous system, affecting multiple neurons.
  • Neuromodulatoren sind chemische Substanzen, die die Arbeitsweise des Nervensystems beeinflussen. Sie können vom Körper selbst produziert werden und sind für die normale, physiologische Arbeitsweise des Gehirns unverzichtbar. Neuromodulatoren sind aber auch zahlreiche pharmakologisch aktive Substanzen, die dem Körper von außen zugeführt werden und als Medikamente oder Drogen wirken.
rdfs:label
  • Neuromodulation
  • Neuromodelação
  • Neuromodulatie
  • Neuromodulation
  • Neuromodulator
  • Neuromodulatore
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