La lattoperossidasi è una perossidasi, un tipo di enzima, che si trova nel latte. Tale enzima possiede attività antimicrobica e antiossidante.La lattoperossidasi è una proteina costituita da una catena di 595 residui amminoacidici avvolta in una struttura sferoidale. La struttura contiene 20 sequenze ad alfa elica di varia lunghezza.

PropertyValue
dbpedia-owl:abstract
  • La lattoperossidasi è una perossidasi, un tipo di enzima, che si trova nel latte. Tale enzima possiede attività antimicrobica e antiossidante.La lattoperossidasi è una proteina costituita da una catena di 595 residui amminoacidici avvolta in una struttura sferoidale. La struttura contiene 20 sequenze ad alfa elica di varia lunghezza.
  • Das Enzym Lactoperoxidase (LPO) kommt in den meisten Tieren vor und wird im Menschen von den Brustdrüsen, Speicheldrüsen und Schleimdrüsen der Bronchien ausgeschieden. Es katalysiert die Oxidation von Phenolen und verschiedenen Anionen durch Wasserstoffperoxid. Die Reaktionsprodukte sind hochreaktive Moleküle, die toxisch auf in den Körper eingedrungene Mikroorganismen wirken. LPO ist daher ein Teil des angeborenen (unspezifischen) Immunsystems und ermöglicht die Neutralisierung von Bakterien in der Milch und anderen Schleimhautsekreten.Unter dem Lactoperoxidase-System versteht man die Kombination aus Lactoperoxidase und dessen ionischen Substraten, dem Wasserstoffperoxid sowie den Oxidationsprodukten.Bekannte Substrate sind Bromid- und Iodid-Ionen, aber auch das Thiocyanat-Ion. Die Produkte der enzymkatalysierten Oxidation sind stark antibakteriell wirksam, vermutlich durch Hemmung der Glucose-Aufnahme.
  • Lactoperoxidase is a peroxidase enzyme secreted from mammary, salivary, and other mucosal glands that functions as a natural antibacterial agent. Lactoperoxidase is a member of the heme peroxidase family of enzymes. In humans, lactoperoxidase is encoded by the LPO gene.Lactoperoxidase catalyzes the oxidation of a number of inorganic and organic substrates by hydrogen peroxide. These substrates include bromide and iodide and therefore lactoperoxidase can be categorised as a haloperoxidase. Another important substrate is thiocyanate. The oxidized products produced through the action of this enzyme have potent bactericidal activities. Lactoperoxidase together with its inorganic ion substrates, hydrogen peroxide, and oxidized products is known as the lactoperoxidase system.The lactoperoxidase system plays an important role in the innate immune system by killing bacteria in milk and mucosal (linings of mostly endodermal origin, covered in epithelium, which are involved in absorption and secretion) secretions hence augmentation of the lactoperoxidase system may have therapeutic applications. Furthermore, addition or augmentation of the lactoperoxidase system has potential applications in controlling bacteria in food and consumer health care products. The lactoperoxidase system does not attack DNA and is not mutagenic. However, under certain conditions, the lactoperoxidase system may contribute to oxidative stress. Furthermore, lactoperoxidase may contribute to the initiation of breast cancer, through its ability to oxidize estrogenic hormones producing free radical intermediates.
  • Laktoperoksydaza (EC 1.11.1.7) – enzym, peroksydaza wydzielana przez gruczołów ślinowe, sutkowe. Jest naturalnym czynnikiem bakteriobójczym. W swej budowie posiada cząsteczkę hemu. U ludzi laktoperoksydaza est kodowana przez gen LPO.Laktoperoksydaza katalizuje utlenianie wielu substratów organicznych i nieorganicznych w obecności nadtlenku wodoru, takiej jak bromki, jodki czy tiocyjanian, które po utlenieniu mają właściwości przeciwbakteryjne. Laktoperoksydaza wraz ze swoimi substratami i produktami znana jest pod nazwą system laktoperoksydazy. System laktoperoksydazy gra ważną rolę w działaniu układ immunologiczny przez zabijanie bakterii w mleku i wydzielinach błon śluzowych.== Przypisy ==
dbpedia-owl:thumbnail
dbpedia-owl:wikiPageExternalLink
dbpedia-owl:wikiPageID
  • 4449191 (xsd:integer)
dbpedia-owl:wikiPageLength
  • 9454 (xsd:integer)
dbpedia-owl:wikiPageOutDegree
  • 42 (xsd:integer)
dbpedia-owl:wikiPageRevisionID
  • 109495254 (xsd:integer)
dbpedia-owl:wikiPageWikiLink
prop-fr:codeGo
  • 4601 (xsd:integer)
prop-fr:cofact
prop-fr:index
  • 1.110000 (xsd:double)
prop-fr:légende
  • Structure d'une lactoperoxydase liée à l'hème
prop-fr:nom
  • Lactoperoxydase
prop-fr:uibmb
  • 1 (xsd:integer)
prop-fr:wikiPageUsesTemplate
dcterms:subject
rdfs:comment
  • La lattoperossidasi è una perossidasi, un tipo di enzima, che si trova nel latte. Tale enzima possiede attività antimicrobica e antiossidante.La lattoperossidasi è una proteina costituita da una catena di 595 residui amminoacidici avvolta in una struttura sferoidale. La struttura contiene 20 sequenze ad alfa elica di varia lunghezza.
  • Lactoperoxidase is a peroxidase enzyme secreted from mammary, salivary, and other mucosal glands that functions as a natural antibacterial agent. Lactoperoxidase is a member of the heme peroxidase family of enzymes. In humans, lactoperoxidase is encoded by the LPO gene.Lactoperoxidase catalyzes the oxidation of a number of inorganic and organic substrates by hydrogen peroxide. These substrates include bromide and iodide and therefore lactoperoxidase can be categorised as a haloperoxidase.
  • Das Enzym Lactoperoxidase (LPO) kommt in den meisten Tieren vor und wird im Menschen von den Brustdrüsen, Speicheldrüsen und Schleimdrüsen der Bronchien ausgeschieden. Es katalysiert die Oxidation von Phenolen und verschiedenen Anionen durch Wasserstoffperoxid. Die Reaktionsprodukte sind hochreaktive Moleküle, die toxisch auf in den Körper eingedrungene Mikroorganismen wirken.
  • Laktoperoksydaza (EC 1.11.1.7) – enzym, peroksydaza wydzielana przez gruczołów ślinowe, sutkowe. Jest naturalnym czynnikiem bakteriobójczym. W swej budowie posiada cząsteczkę hemu. U ludzi laktoperoksydaza est kodowana przez gen LPO.Laktoperoksydaza katalizuje utlenianie wielu substratów organicznych i nieorganicznych w obecności nadtlenku wodoru, takiej jak bromki, jodki czy tiocyjanian, które po utlenieniu mają właściwości przeciwbakteryjne.
rdfs:label
  • Lactoperoxydase
  • Lactoperoxidase
  • Lactoperoxidase
  • Laktoperoksydaza
  • Lattoperossidasi
owl:sameAs
http://www.w3.org/ns/prov#wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbpedia-owl:wikiPageRedirects of
is dbpedia-owl:wikiPageWikiLink of
is foaf:primaryTopic of