Диметилфумарат — диметиловый эфир фумаровой кислоты. Находит применения для лечения некоторых кожных заболеваний, а также в качестве биоцида (прежде всего, фунгицида).

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  • Диметилфумарат — диметиловый эфир фумаровой кислоты. Находит применения для лечения некоторых кожных заболеваний, а также в качестве биоцида (прежде всего, фунгицида).
  • A dimetil-fumarát a fumársav metil észtere.
  • Dimethyl fumarate (DMF) is the methyl ester of fumaric acid. DMF was initially recognized as a very effective hypoxic cell radiosensitizer. Later, DMF combined with three other fumaric acid esters (FAE) was licensed in Germany as oral therapy for psoriasis (trade name Fumaderm). Other diseases, such as necrobiosis lipoidica, granuloma annulare, and sarcoidosis were also found to respond to treatment with DMF in case reports or small patient series. Phase III clinical trials found that DMF (BG-12) successfully reduced relapse rate and increased time to progression of disability in multiple sclerosis (trade name Tecfidera). DMF is thought to have immunomodulatory properties without significant immunosuppression.In a non-medical use, DMF was applied as a biocide in furniture or shoes to prevent growths of mold during storage or transport in a humid climate. However, due to incidences of allergic reactions after skin contact the European Union banned DMF in consumer products since 1998, and since January 2009 the import of products containing DMF was also banned.
  • Dimethylfumaraat is de dimethylester van fumaarzuur.
  • Vorlage:Infobox Chemikalie/Summenformelsuche vorhandenFumarsäuredimethylester, auch Dimethylfumarat, ist der Diester der Fumarsäure mit dem Alkohol Methanol. Dieser und andere Ester der Fumarsäure werden als Arzneistoffe zur Behandlung der Multiplen Sklerose und der Psoriasis eingesetzt. Dimethylfumarat werden immunmodulatorische und antioxidative Eigenschaften zugeschrieben.In einer nicht-medizinischen Verwendung wird Dimethylfumarat als Biozid zur Behandlung von Kleidung, Schuhen und Möbeln gegen Schimmelpilzbefall eingesetzt. Seit dem 1. Mai 2009 gilt in der gesamten EU allerdings ein Verwendungsverbot als Biozid wegen gehäufter Auslösung allergischer Reaktionen.
  • El dimetilfumarato es un éster del ácido fumárico.
  • Il dimetilfumarato o DMF è l'estere metilico dell'acido fumarico.È un composto nocivo usato come agente antimuffa, il cui uso è proibito nell'Unione europea.Trova impiego anche come medicinale nella cura della psoriasi.
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  • Fumarate de diméthyle
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  • Диметилфумарат — диметиловый эфир фумаровой кислоты. Находит применения для лечения некоторых кожных заболеваний, а также в качестве биоцида (прежде всего, фунгицида).
  • A dimetil-fumarát a fumársav metil észtere.
  • Dimethylfumaraat is de dimethylester van fumaarzuur.
  • El dimetilfumarato es un éster del ácido fumárico.
  • Il dimetilfumarato o DMF è l'estere metilico dell'acido fumarico.È un composto nocivo usato come agente antimuffa, il cui uso è proibito nell'Unione europea.Trova impiego anche come medicinale nella cura della psoriasi.
  • Dimethyl fumarate (DMF) is the methyl ester of fumaric acid. DMF was initially recognized as a very effective hypoxic cell radiosensitizer. Later, DMF combined with three other fumaric acid esters (FAE) was licensed in Germany as oral therapy for psoriasis (trade name Fumaderm). Other diseases, such as necrobiosis lipoidica, granuloma annulare, and sarcoidosis were also found to respond to treatment with DMF in case reports or small patient series.
  • Vorlage:Infobox Chemikalie/Summenformelsuche vorhandenFumarsäuredimethylester, auch Dimethylfumarat, ist der Diester der Fumarsäure mit dem Alkohol Methanol. Dieser und andere Ester der Fumarsäure werden als Arzneistoffe zur Behandlung der Multiplen Sklerose und der Psoriasis eingesetzt.
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  • Fumarate de diméthyle
  • Dimethyl fumarate
  • Dimethylfumaraat
  • Dimetil-fumarát
  • Dimetilfumarato
  • Dimetilfumarato
  • Fumarsäuredimethylester
  • Диметилфумарат
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