About: dbpedia-fr:Vinblastine

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An Entity of Type : dbo:ChemicalSubstance, within Data Space : fr.dbpedia.org associated with source document(s)

Attributes	Values
rdf:type	Thing chemical compound Chemical compound dul:ChemicalObject dbo:ChemicalSubstance
rdfs:label	Vinblastine (fr) Vinblastin (de) Vinblastina (es) Winblastyna (pl) Винбластин (ru) ビンブラスチン (ja) 长春碱 (zh)
rdfs:comment	La vinblastine et son sel, le sulfate de vinblastine sont des toxines extraites de la pervenche de Madagascar (Catharanthus roseus). Elle est formée par la plante en associant la et la . La vinblastine est utilisée à des fins médicales, notamment dans le traitement du cancer du poumon, cancer du sein et les lymphomes. C'est un poison du fuseau mitotique qui inhibe la polymérisation de la tubuline en microtubules, ce qui bloque la division cellulaire provoquant préférentiellement la mort de la cellule tumorale. (fr)
rdfs:seeAlso	http://echa.europa.eu/substance-information/-/substanceinfo/100.011.577 http://www.hmdb.ca/metabolites/HMDB0014710 https://commons.wikimedia.org/wiki/Category:Vinblastine https://tools.wmflabs.org/magnustools/cas.php?cas=865-21-4 https://www.britannica.com/science/vinblastine https://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pccompound&term=%22JXLYSJRDGCGARV-XQKSVPLYSA-N%22InChIKey http://toxnet.nlm.nih.gov/cgi-bin/sis/search2/r?dbs+hsdb:@term+@DOCNO+3263 http://www.whocc.no/atc_ddd_index/?code=L01CA01 http://www.drugbank.ca/drugs/DB00570 https://comptox.epa.gov/dashboard/DTXSID8021430 http://bioportal.bioontology.org/ontologies/RXNORM?p=classes&conceptid=11198 http://chemapps.stolaf.edu/jmol/jmol.php?&model=InChI=InChI=1S/C46H58N4O9/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3/t28-,37+,38-,39-,42+,43-,44-,45+,46+/m1/s1 http://chemapps.stolaf.edu/jmol/jmol.php?model=CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=5V9KLZ54CY http://kanaya.naist.jp/knapsack_jsp/information.jsp?sname=C_ID&word=C00001781 http://lod.nal.usda.gov/nalt/10471 http://www.simolecule.com/cdkdepict/depict/bow/svg?smi=CCC@@1(CC@@H2CC@@(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C@78CCN9C@H7C@@(C=CC9)(C@H(C@@(C@@H8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O&zoom=2.0&annotate=cip https://mor.nlm.nih.gov/RxNav/search?searchBy=NUI&searchTerm=N0000148055 http://chemdb.niaid.nih.gov/CompoundDetails.aspx?AIDSNO=002673
sameAs	dbr:Vinblastine dbpedia-commons:Category:Vinblastine wikidata:Q282629 dbpedia-ar:فينبلاستين dbpedia-cy:Finblastin dbpedia-de:Vinblastin dbpedia-es:Vinblastina dbpedia-fa:وینبلاستین dbpedia-fi:Vinblastiini dbpedia-hu:Vinblasztin http://hy.dbpedia.org/resource/Վինբլաստին dbpedia-it:Vinblastina dbpedia-ja:ビンブラスチン http://or.dbpedia.org/resource/ଭିନବ୍ଲାସ୍ଟିନ dbpedia-pl:Winblastyna dbpedia-pt:Vimblastina dbpedia-ro:Vinblastină dbpedia-ru:Винбластин dbpedia-sh:Vinblastin dbpedia-sl:Vinblastin dbpedia-sr:Vinblastin dbpedia-uk:Вінбластин dbpedia-vi:Vinblastine dbpedia-zh:长春碱 http://azb.dbpedia.org/resource/وینبلاستین http://purl.obolibrary.org/obo/CHEBI_27375 http://rdf.ebi.ac.uk/resource/chembl/molecule/CHEMBL22969 http://g.co/kg/m/07cllr https://www.kegg.jp/entry/D08675 http://globalwordnet.org/ili/i60861 http://id.nlm.nih.gov/mesh/D014747 http://id.nlm.nih.gov/mesh/D03.132.436.681.827.650 http://id.nlm.nih.gov/mesh/D03.633.100.473.402.681.827.650 http://ma-graph.org/entity/2777132456 http://rdf.chemspider.com/211446 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID241903
Wikipage page ID	658804 (xsd:integer)
Wikipage revision ID	184904077 (xsd:integer)
dbo:wikiPageWikiLink	category-fr:Médicament_essentiel_listé_par_l'OMS category-fr:Inhibiteur_de_microtubule category-fr:Poison_du_fuseau_mitotique dbpedia-fr:Alcaloïde dbpedia-fr:Cancer_de_l'ovaire dbpedia-fr:Cancer_de_la_vessie dbpedia-fr:Cancer_du_poumon dbpedia-fr:Cancer_du_rein dbpedia-fr:Cancer_du_sein dbpedia-fr:Cancer_du_testicule category-fr:Polyol Choriocarcinoma dbpedia-fr:Classe_ATC_L01 dbpedia-fr:Dictionnaire_Vidal Cell division dbpedia-fr:Fuseau_mitotique dbpedia-fr:Histiocytose_langerhansienne Lymphoma Hodgkin lymphoma Non-Hodgkin lymphoma dbpedia-fr:Organisation_mondiale_de_la_santé dbpedia-fr:Pervenche_de_Madagascar Polymerization Sulfate Toxin dbpedia-fr:Tubuline dbpedia-fr:Maladie_de_Kaposi Microtubule dbpedia-fr:Catharanthine dbpedia-fr:Vindoline

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