About: Ciclosporin

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An Entity of Type : dbo:ChemicalSubstance, within Data Space : fr.dbpedia.org associated with source document(s)

Attributes	Values
rdf:type	Thing chemical compound Chemical compound dul:ChemicalObject dbo:ChemicalSubstance
rdfs:label	Ciclosporine (fr) Ciclosporin (en) Ciclosporina (ca) Ciclosporina (es) Ciclosporine (nl) Ciklosporin (sv) Siklosporien (af) سيكلوسبورين (ar) シクロスポリン (ja)
rdfs:comment	La ciclosporine (selon la dénomination commune internationale, mais aussi appelée cyclosporine) est un agent immunosuppresseur dont l'utilisation thérapeutique, dès le début des années 1980, a permis un essor considérable du domaine de la transplantation d'organes en prévenant le rejet aigu des allogreffes. Aujourd'hui encore largement employée en transplantation (peau, cœur, rein, poumons, pancréas, moelle osseuse, intestin grêle), quoique concurrencée par des molécules plus récentes, la ciclosporine a également des applications en dermatologie et dans le traitement de certaines maladies auto-immunes. (fr)
rdfs:seeAlso	http://echa.europa.eu/substance-information/-/substanceinfo/100.119.569 http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=1024 http://www.universalis.fr/encyclopedie/ciclosporine-cyclosporine https://commons.wikimedia.org/wiki/Category:Ciclosporin https://tools.wmflabs.org/magnustools/cas.php?cas=59865-13-3 https://www.britannica.com/science/cyclosporine https://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pccompound&term=%22PMATZTZNYRCHOR-CGLBZJNRSA-N%22InChIKey https://www.quora.com/topic/Cyclosporine http://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/EOV http://toxnet.nlm.nih.gov/cgi-bin/sis/search2/r?dbs+hsdb:@term+@DOCNO+6881 http://www.whocc.no/atc_ddd_index/?code=L04AD01 http://www.whocc.no/atc_ddd_index/?code=S01XA18 http://www.drugbank.ca/drugs/DB00091 https://comptox.epa.gov/dashboard/DTXSID0020365 http://bioportal.bioontology.org/ontologies/RXNORM?p=classes&conceptid=3008 http://chemapps.stolaf.edu/jmol/jmol.php?&model=InChI=InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78) http://chemapps.stolaf.edu/jmol/jmol.php?model=CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=83HN0GTJ6D http://kanaya.naist.jp/knapsack_jsp/information.jsp?sname=C_ID&word=C00001517 http://lod.nal.usda.gov/nalt/148746 http://www.iedb.org/epitope/451241 http://www.simolecule.com/cdkdepict/depict/bow/svg?smi=CCC@H1C(=O)N(CC(=O)N(C@H(C(=O)NC@H(C(=O)N(C@H(C(=O)NC@H(C(=O)NC@@H(C(=O)N(C@H(C(=O)N(C@H(C(=O)N(C@H(C(=O)N(C@H(C(=O)N1)C@@H(C@H(C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C&zoom=2.0&annotate=cip https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&chemnameboolean=and&outputformat=html&searchlist=290193&Submit=Submit https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&chemnameboolean=and&outputformat=html&searchlist=758194&Submit=Submit https://mor.nlm.nih.gov/RxNav/search?searchBy=NUI&searchTerm=N0000147064 https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&code=C0010592 http://www.wikiskripta.eu/index.php?curid=12366
sameAs	Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin Ciclosporin
Wikipage page ID	2870578 (xsd:integer)
Wikipage revision ID	188186769 (xsd:integer)
dbo:wikiPageWikiLink	category-fr:Cancérogène_du_groupe_1_du_CIRC category-fr:Médicament_essentiel_listé_par_l'OMS category-fr:Néphrotoxine 1983 2002 dbpedia-fr:Acide_aminé

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