About: Astemizole

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An Entity of Type : dbo:ChemicalSubstance, within Data Space : fr.dbpedia.org associated with source document(s)

Attributes	Values
rdf:type	Thing chemical compound Chemical compound dul:ChemicalObject dbo:ChemicalSubstance
rdfs:label	Astémizole (fr) Astemizol (de) Astemizol (pl) Astemizole (en) Astemizolo (it) أستيميزول (ar)
rdfs:comment	L'astémizole, distribué sous la marque Hismanal, est un antihistaminique de deuxième génération à action longue durée qui a été retiré du marché dans la plupart des pays en raison d'effets indésirables rares mais potentiellement fatals (augmentation de l'intervalle QTc et arythmie liée provoquée par le blocage des canaux hERG). L'astémizole est dégradé par le cytochrome P450 3A4 (CYP3A4), présent dans le foie et les intestins. (fr)
rdfs:seeAlso	http://echa.europa.eu/substance-information/-/substanceinfo/100.065.837 http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2603 https://commons.wikimedia.org/wiki/Category:Astemizole https://tools.wmflabs.org/magnustools/cas.php?cas=68844-77-9 https://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pccompound&term=%22GXDALQBWZGODGZ-UHFFFAOYSA-N%22InChIKey http://toxnet.nlm.nih.gov/cgi-bin/sis/search2/r?dbs+hsdb:@term+@DOCNO+6799 http://www.whocc.no/atc_ddd_index/?code=R06AX11 http://www.drugbank.ca/drugs/DB00637 https://comptox.epa.gov/dashboard/DTXSID9020110 http://bioportal.bioontology.org/ontologies/RXNORM?p=classes&conceptid=42328 http://chemapps.stolaf.edu/jmol/jmol.php?&model=InChI=InChI=1S/C28H31FN4O/c1-34-25-12-8-21(9-13-25)14-17-32-18-15-24(16-19-32)30-28-31-26-4-2-3-5-27(26)33(28)20-22-6-10-23(29)11-7-22/h2-13,24H,14-20H2,1H3,(H,30,31) http://chemapps.stolaf.edu/jmol/jmol.php?model=COC1=CC=C(C=C1)CCN2CCC(CC2)NC3=NC4=CC=CC=C4N3CC5=CC=C(C=C5)F http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=7HU6337315 https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&chemnameboolean=and&outputformat=html&searchlist=329963&Submit=Submit https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&chemnameboolean=and&outputformat=html&searchlist=759570&Submit=Submit https://mor.nlm.nih.gov/RxNav/search?searchBy=NUI&searchTerm=N0000147536 https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&code=C0085170
sameAs	Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole Astemizole
Wikipage page ID	8050834 (xsd:integer)
Wikipage revision ID	161115337 (xsd:integer)
dbo:wikiPageWikiLink	Edema category-fr:Antihistaminique_H1 dbpedia-fr:Anticholinergique dbpedia-fr:Antihistaminique dbpedia-fr:Antiprurigineux Blood–brain barrier dbpedia-fr:Butyrophénone CYP3A4 dbpedia-fr:Catabolisme category-fr:Benzimidazole category-fr:Fluorobenzène category-fr:Guanidine category-fr:Médicament_retiré_du_marché category-fr:Méthoxybenzène category-fr:Pipéridine dbpedia-fr:Chloroquine Liver dbpedia-fr:HERG Haloperidol dbpedia-fr:Intestin Antipsychotic Malaria Prion Itch Arrhythmia dbpedia-fr:Maladie_d'Alzheimer dbpedia-fr:Maladie_de_Creutzfeldt-Jakob dbpedia-fr:Matière_fécale_humaine
page length (characters) of wiki page	10230 (xsd:nonNegativeInteger)
EINECS number	272-441-9
dct:subject	category-fr:Antihistaminique_H1 category-fr:Benzimidazole category-fr:Fluorobenzène category-fr:Guanidine category-fr:Médicament_retiré_du_marché category-fr:Méthoxybenzène category-fr:Pipéridine
foaf:name	(fr)

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