About: Hydroxycarbamide

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An Entity of Type : dbo:ChemicalSubstance, within Data Space : fr.dbpedia.org associated with source document(s)

Attributes	Values
rdf:type	Thing chemical compound Chemical compound dul:ChemicalObject dbo:ChemicalSubstance
rdfs:label	Hydroxyurée (fr) Hydroksykarbamid (pl) Hydroxycarbamide (en) N-idrossiurea (it) Гидроксикарбамид (ru) هيدروكسي يوريا (ar) ヒドロキシカルバミド (ja)
rdfs:comment	L'hydroxyurée, ou hydroxycarbamide (CH4N2O2), a été synthétisé pour la première fois en 1869, mais l'intérêt de ce produit dans les leucémies ne s'est développé qu'au cours des années 1960. L'hydroxyurée diffère de l'urée par la présence d'un groupe hydroxyle sur l'un des atomes d'azote. Cette molécule agit sur la ribonucléotide réductase. Il s'agit de l'enzyme clé de la transformation des quatre ribonucléotides en désoxyribonucléotides essentiels à la synthèse de l'ADN. (fr)
rdfs:seeAlso	http://www.drugbank.ca/drugs/DB01005 http://bioportal.bioontology.org/ontologies/RXNORM?p=classes&conceptid=5552 http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=X6Q56QN5QC https://mor.nlm.nih.gov/RxNav/search?searchBy=NUI&searchTerm=N0000146101 http://echa.europa.eu/substance-information/-/substanceinfo/100.004.384 http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6822 http://www.hmdb.ca/metabolites/HMDB0015140 https://commons.wikimedia.org/wiki/Category:Hydroxyurea https://tools.wmflabs.org/magnustools/cas.php?cas=127-07-1 https://www.britannica.com/science/hydroxyurea https://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pccompound&term=%22VSNHCAURESNICA-UHFFFAOYSA-N%22InChIKey http://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/NHY http://toxnet.nlm.nih.gov/cgi-bin/sis/search2/r?dbs+hsdb:@term+@DOCNO+6887 http://www.whocc.no/atc_ddd_index/?code=L01XX05 https://comptox.epa.gov/dashboard/DTXSID6025438 http://chemapps.stolaf.edu/jmol/jmol.php?&model=InChI=InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4) http://chemapps.stolaf.edu/jmol/jmol.php?model=C(=O)(N)NO https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&chemnameboolean=and&outputformat=html&searchlist=32065&Submit=Submit https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&chemnameboolean=and&outputformat=html&searchlist=757072&Submit=Submit https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&code=C0020402 https://www.patientslikeme.com/treatments/show/hydroxyurea http://chemdb.niaid.nih.gov/CompoundDetails.aspx?AIDSNO=006310
sameAs	Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide Hydroxycarbamide
Wikipage page ID	1297099 (xsd:integer)
Wikipage revision ID	166662225 (xsd:integer)
dbo:wikiPageWikiLink	category-fr:Médicament_essentiel_listé_par_l'OMS category-fr:Antibiotique_antitumoral dbpedia-fr:1869 dbpedia-fr:Acide_désoxyribonucléique 1960s Nitrogen category-fr:Carbamide Sickle cell disease dbpedia-fr:Désoxyribonucléotide Hydroxylamine Hydroxy group dbpedia-fr:Leucémie dbpedia-fr:Organisation_mondiale_de_la_santé Oxime Ribonucleotide Ribonucleotide reductase Tautomer Nitroglycerin
page length (characters) of wiki page	6648 (xsd:nonNegativeInteger)
EINECS number	204-821-7
dct:subject	category-fr:Médicament_essentiel_listé_par_l'OMS category-fr:Antibiotique_antitumoral category-fr:Carbamide
foaf:name	Hydroxyurée (fr)
prop-fr:wikiPageUsesTemplate	dbpedia-fr:Modèle:Date-

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